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. 2003 Jul 2;125(26):7792-3.
doi: 10.1021/ja0349857.

C-H activation/borylation/oxidation: a one-pot unified route to meta-substituted phenols bearing ortho-/para-directing groups

Robert E Maleczka Jr  1 , Feng Shi, Daniel Holmes, Milton R Smith 3rd
Affiliations

C-H activation/borylation/oxidation: a one-pot unified route to meta-substituted phenols bearing ortho-/para-directing groups

Robert E Maleczka Jr et al. J Am Chem Soc. .

Abstract

An efficient one-pot C-H activation/borylation/oxidation protocol for the preparation of phenols is described. This method is particularly attractive for the generation of meta-substituted phenols bearing ortho-/para-directing groups, as such substrates are difficult to access by other phenol syntheses.

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