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Review
. 1992 Nov;13(11):431-3.
doi: 10.1016/0167-5699(92)90068-I.

CD40 and its ligand, an essential ligand-receptor pair for thymus-dependent B-cell activation

R J Noelle  1 , J A Ledbetter, A Aruffo
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Free article
Review

CD40 and its ligand, an essential ligand-receptor pair for thymus-dependent B-cell activation

R J Noelle et al. Immunol Today. 1992 Nov.
Free article

Abstract

The discovery of CD40 and its ligand, gp39, have created new perspectives on the activation of resting B cells by TH cells. Here, Randolph Noelle, Jeffrey Ledbetter and Alejandro Aruffo describe how these molecules were characterized and, from recent findings, examine their relevance to immune activation.

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