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. 2003 Jul 1;31(13):3525-6.
doi: 10.1093/nar/gkg623.

MAVID multiple alignment server

Nicolas Bray  1 , Lior Pachter
Affiliations

MAVID multiple alignment server

Nicolas Bray et al. Nucleic Acids Res. .

Abstract

MAVID is a multiple alignment program suitable for many large genomic regions. The MAVID web server allows biomedical researchers to quickly obtain multiple alignments for genomic sequences and to subsequently analyse the alignments for conserved regions. MAVID has been successfully used for the alignment of closely related species such as primates and also for the alignment of more distant organisms such as human and fugu. The server is fast, capable of aligning hundreds of kilobases in less than a minute. The multiple alignment is used to build a phylogenetic tree for the sequences, which is subsequently used as a basis for identifying conserved regions in the alignment. The server can be accessed at http://baboon.math.berkeley.edu/mavid/.

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Figures

Figure 1
Figure 1
Examples of output from the MAVID server for four sequences (human, mouse, rat and fugu) containing the CAV1 gene. (A) Pairwise VISTA plots from the projection of the multiple alignment onto the human sequence. (B) The phylogenetic tree constructed from the alignment. (C) A region from the multiple alignment.
See this image and copyright information in PMC

References

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