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. 2003 Jul 4;17(10):1572-4.
doi: 10.1097/00002030-200307040-00023.

The effect of lamivudine on the replication of hepatitis B virus in HIV-infected patients depends on the host immune status (CD4 cell count)

Margje Haverkamp  1 , Maarten Smit, Annemarie Weersink, Charles A Boucher, Andy I Hoepelman
Affiliations

The effect of lamivudine on the replication of hepatitis B virus in HIV-infected patients depends on the host immune status (CD4 cell count)

Margje Haverkamp et al. AIDS. .

Abstract

We retrospectively analysed the effect of lamivudine on hepatitis B virus (HBV) in HIV-co-infected patients. In this small study we document a CD4 cell-dependent response on HBV replication with lamivudine therapy. In this respect, hepatitis B may be considered an opportunistic infection. Our finding may have important clinical consequences, and large prospective studies are necessary to investigate this further.

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