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. 2003 Jul 3;46(14):2813-5.
doi: 10.1021/jm030213+.

Design, synthesis, and evaluation of novel boronic-chalcone derivatives as antitumor agents

Srinivas K Kumar  1 , Erin Hager, Catherine Pettit, Hallur Gurulingappa, Nancy E Davidson, Saeed R Khan
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Design, synthesis, and evaluation of novel boronic-chalcone derivatives as antitumor agents

Srinivas K Kumar et al. J Med Chem. .

Abstract

A series of boronic-chalcone derivatives were synthesized and tested for antitumor activity against human breast cancer cell lines. The results show the boronic-chalcones are more toxic to breast cancer cells compared to normal breast cells than other known chalcones.

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