Review
doi: 10.1016/s1043-2760(03)00086-9.
The ins and outs of fatty acids on the pancreatic beta cell
Affiliations
- PMID: 12826323
- DOI: 10.1016/s1043-2760(03)00086-9
Item in Clipboard
Review
The ins and outs of fatty acids on the pancreatic beta cell
Trends Endocrinol Metab.
2003 Jul.
No abstract available
Comment on
-
The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids.J Biol Chem. 2003 Mar 28;278(13):11303-11. doi: 10.1074/jbc.M211495200. Epub 2002 Dec 19. J Biol Chem. 2003. PMID: 12496284
-
A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs.Biochem Biophys Res Commun. 2003 Feb 7;301(2):406-10. doi: 10.1016/s0006-291x(02)03064-4. Biochem Biophys Res Commun. 2003. PMID: 12565875
-
Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.Nature. 2003 Mar 13;422(6928):173-6. doi: 10.1038/nature01478. Epub 2003 Feb 23. Nature. 2003. PMID: 12629551
Similar articles
-
Expression of fatty acid binding proteins 3 and 5 genes in rat pancreatic islets and INS-1E cells: regulation by fatty acids and glucose.Islets. 2010 May-Jun;2(3):174-84. doi: 10.4161/isl.2.3.11454. Islets. 2010. PMID: 21099311
-
Long term exposure to fatty acids and ketones inhibits B-cell functions in human pancreatic islets of Langerhans.J Clin Endocrinol Metab. 1995 May;80(5):1584-90. doi: 10.1210/jcem.80.5.7745004. J Clin Endocrinol Metab. 1995. PMID: 7745004
-
Augmentation of Ca2+-stimulated insulin release by glucose and long-chain fatty acids in rat pancreatic islets: free fatty acids mimic ATP-sensitive K+ channel-independent insulinotropic action of glucose.Diabetes. 1999 Aug;48(8):1543-9. doi: 10.2337/diabetes.48.8.1543. Diabetes. 1999. PMID: 10426371
-
Direct and indirect actions of nutrients in the regulation of insulin secretion from the pancreatic beta cells.Proc Nutr Soc. 1991 Dec;50(3):559-66. doi: 10.1079/pns19910069. Proc Nutr Soc. 1991. PMID: 1809964 Review. No abstract available.
-
[Fatty acids and beta cells].Diabetes Metab. 2000 Jun;26 Suppl 3:6-9. Diabetes Metab. 2000. PMID: 10945143 Review. French.
Cited by
-
Lipotoxicity and β-Cell Failure in Type 2 Diabetes: Oxidative Stress Linked to NADPH Oxidase and ER Stress.Cells. 2021 Nov 26;10(12):3328. doi: 10.3390/cells10123328. Cells. 2021. PMID: 34943836 Free PMC article. Review.
-
G protein-coupled receptors and insulin secretion: 119 and counting.Endocrinology. 2007 Jun;148(6):2598-600. doi: 10.1210/en.2007-0336. Endocrinology. 2007. PMID: 17507578 Free PMC article. No abstract available.
-
The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding.Diabetes. 2008 Sep;57(9):2432-7. doi: 10.2337/db08-0553. Epub 2008 Jun 16. Diabetes. 2008. PMID: 18559658 Free PMC article.
-
Chronic glucolipotoxic conditions in pancreatic islets impair insulin secretion due to dysregulated calcium dynamics, glucose responsiveness and mitochondrial activity.BMC Cell Biol. 2013 Jul 1;14:31. doi: 10.1186/1471-2121-14-31. BMC Cell Biol. 2013. PMID: 23815372 Free PMC article.
-
A dual action of saturated fatty acids on electrical activity in rat pancreatic β-cells. Role of volume-regulated anion channel and KATP channel currents.J Physiol. 2011 Mar 15;589(Pt 6):1307-16. doi: 10.1113/jphysiol.2010.200741. Epub 2011 Jan 17. J Physiol. 2011. PMID: 21242256 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
