Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2003;16(2):141-57.
doi: 10.1089/088282403322017884.

The hypothalamic-pituitary-adrenal axis and viral infection

Michael Bailey  1 , Harald Engler, John Hunzeker, John F Sheridan
Affiliations
Review

The hypothalamic-pituitary-adrenal axis and viral infection

Michael Bailey et al. Viral Immunol. 2003.

Abstract

The hypothalamic-pituitary-adrenal (HPA) axis plays an important immunomodulatory role during viral infection. Activation of the HPA axis ultimately leads to elevated plasma levels of glucocorticoid (GC) hormones with the ability to mediate adaptive behavioral, metabolic, cardiovascular and immune system effects. In this review, we focus on the modulation of anti-viral immunity and viral pathogenesis by the HPA axis.

PubMed Disclaimer

Publication types

LinkOut - more resources