[Amyloidosis localized in the seminal vesicles: clinico-pathological review of 8 cases diagnosed in surgical specimens]

Abstract

Objectives: Clinical and pathological study of eight cases of localized amyloidosis of the seminal vesicles. Review of the literature.

Methods: Immunohistochemical and histochemical study in surgical specimens.

Results: Two of the eight cases studied for amyloidosis in seminal vesicles, were obtained from radical prostatectomy specimens; patients had prior androgen deprivation therapy for two months. Four cases were obtained from radical cistoprostatectomy specimens because of urothelial carcinoma and the last two cases were diagnosed by transrectal prostatic needle biopsy which including a portion of seminal vesicle. Amyloidosis of seminal the vesicle is permanganate-sensitive; A-Amyloid, laminin, amyloid P protein and collagen IV negative.

Conclusion: Localized amyloidosis ot the seminal vesicle is not an unusual finding. The incidence increases with age. The histochemical and immunohistochemical features are different from other amyloid deposits.