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Review
. 2003 Jun;13(3):309-16.
doi: 10.1016/s0959-440x(03)00066-6.

RNA folding: models and perspectives

Tobin R Sosnick  1 , Tao Pan
Affiliations
Review

RNA folding: models and perspectives

Tobin R Sosnick et al. Curr Opin Struct Biol. 2003 Jun.

Abstract

Intrinsic events during RNA folding include conformational search and metal ion binding. Several experimentally testable models have been proposed to explain how large ribozymes accomplish folding. Future challenges include the validation of these models, and the correlation of experimental results and theoretical simulations.

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