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Review
. 2003;50(2):337-65.

The structure of the Ca2+-ATPase of sarcoplasmic reticulum

Affiliations
  • PMID: 12833162
Review

The structure of the Ca2+-ATPase of sarcoplasmic reticulum

Anthony N Martonosi et al. Acta Biochim Pol. 2003.

Abstract

In this article the morphology of sarcoplasmic reticulum, classification of Ca(2+)-ATPase (SERCA) isoenzymes presented in this membrane system, as well as their topology will be reviewed. The focus is on the structure and interactions of Ca(2+)-ATPase determined by electron and X-ray crystallography, lamellar X-ray and neutron diffraction analysis of the profile structure of Ca(2+)-ATPase in sarcoplasmic reticulum multilayers. In addition, targeting of the Ca(2+)-ATPase to the sarcoplasmic reticulum is discussed.

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