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Review
. 2003 Jul;3(7):517-25.
doi: 10.1038/nrc1120.

Curing metastatic cancer: lessons from testicular germ-cell tumours

John R W Masters  1 , Beate Köberle
Affiliations
Review

Curing metastatic cancer: lessons from testicular germ-cell tumours

John R W Masters et al. Nat Rev Cancer. 2003 Jul.

Abstract

Most metastatic cancers are fatal. More than 80% of patients with metastatic testicular germ-cell tumours (TGCTs), however, can be cured using cisplatin-based combination chemotherapy. Why are TGCTs more sensitive to chemotherapeutics than most other tumour types? Answers to this question could lead to new treatments for metastatic cancers.

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