HIV vaccines 1983-2003
- PMID: 12835708
- DOI: 10.1038/nm0703-874
HIV vaccines 1983-2003
Abstract
Twenty years after the discovery of HIV, there is still no vaccine. This year, an envelope vaccine aimed at stimulating neutralizing antibodies was unable to protect against infection in phase 3 trials. But more than 20 HIV vaccines designed to stimulate T-cell responses are being developed. Will any of them work?
Similar articles
-
Durable HIV-1 antibody and T-cell responses elicited by an adjuvanted multi-protein recombinant vaccine in uninfected human volunteers.Vaccine. 2007 Jan 5;25(3):510-8. doi: 10.1016/j.vaccine.2006.07.050. Epub 2006 Aug 10. Vaccine. 2007. PMID: 17049679 Clinical Trial.
-
New hope for an AIDS vaccine.Nat Rev Immunol. 2002 Apr;2(4):239-50. doi: 10.1038/nri776. Nat Rev Immunol. 2002. PMID: 12001995 Review.
-
HIV/AIDS vaccines: 2007.Clin Pharmacol Ther. 2007 Dec;82(6):686-93. doi: 10.1038/sj.clpt.6100408. Epub 2007 Oct 31. Clin Pharmacol Ther. 2007. PMID: 17971817 Review.
-
Induction of neutralizing antibodies and Th1-polarized and CD4-independent CD8+ T-cell responses following delivery of human immunodeficiency virus type 1 Tat protein by recombinant adenylate cyclase of Bordetella pertussis.J Virol. 2005 Aug;79(15):9872-84. doi: 10.1128/JVI.79.15.9872-9884.2005. J Virol. 2005. PMID: 16014948 Free PMC article.
-
Phase 1 clinical trials of the National Institutes of Health Vaccine Research Center HIV/AIDS candidate vaccines.J Infect Dis. 2006 Dec 15;194(12):1625-7. doi: 10.1086/509263. Epub 2006 Nov 8. J Infect Dis. 2006. PMID: 17109331 No abstract available.
Cited by
-
Induction of CD8+ cells able to suppress CCR5-tropic simian immunodeficiency virus SIVmac239 replication by controlled infection of CXCR4-tropic simian-human immunodeficiency virus in vaccinated rhesus macaques.J Virol. 2007 Nov;81(21):11640-9. doi: 10.1128/JVI.01475-07. Epub 2007 Aug 29. J Virol. 2007. PMID: 17728225 Free PMC article.
-
Human immunodeficiency virus type 1-specific immune responses in primates upon sequential immunization with adenoviral vaccine carriers of human and simian serotypes.J Virol. 2004 Jul;78(14):7392-9. doi: 10.1128/JVI.78.14.7392-7399.2004. J Virol. 2004. PMID: 15220412 Free PMC article.
-
The nucleocapsid protein of Rift Valley fever virus is a potent human CD8+ T cell antigen and elicits memory responses.PLoS One. 2013;8(3):e59210. doi: 10.1371/journal.pone.0059210. Epub 2013 Mar 18. PLoS One. 2013. PMID: 23527138 Free PMC article.
-
Strategies and mechanisms for host and pathogen survival in acute and persistent viral infections.Proc Natl Acad Sci U S A. 2004 Oct 5;101 Suppl 2(Suppl 2):14560-6. doi: 10.1073/pnas.0404758101. Epub 2004 Aug 5. Proc Natl Acad Sci U S A. 2004. PMID: 15297608 Free PMC article. Review.
-
Enhanced detection of human immunodeficiency virus type 1 (HIV-1) Nef-specific T cells recognizing multiple variants in early HIV-1 infection.J Virol. 2007 May;81(10):5225-37. doi: 10.1128/JVI.02564-06. Epub 2007 Feb 28. J Virol. 2007. PMID: 17329342 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources