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. 2003 Jul;74(5):486-8.
doi: 10.1016/s0367-326x(03)00124-2.

Evaluation of analgesic effect of Datura fastuosa leaves and seed extracts

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Evaluation of analgesic effect of Datura fastuosa leaves and seed extracts

A A Abena et al. Fitoterapia. 2003 Jul.

Abstract

The aqueous extracts of Datura fastuosa leaves and seeds were evaluated for the analgesic effect on acetic acid-induced writhing and hot plate reaction in mice. According to the results, D. fastuosa leaves and seeds extracts at oral doses of 400 and 800 mg/kg are effective as analgesic. The analgesic activity of leaf extract is reduced by naloxone but not that of seed extract.

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