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Review
. 2003 Jun;10(6):481-6.
doi: 10.1016/s1074-5521(03)00127-3.

The platelet as a model for chemical genetics

Robert Flaumenhaft  1 , Derek S Sim
Affiliations
Review

The platelet as a model for chemical genetics

Robert Flaumenhaft et al. Chem Biol. 2003 Jun.

Abstract

Chemical genetics is an emerging strategy in chemical biology that promises to bring the power of true genetics to mammalian systems and facilitate the transfer of biological discoveries to therapeutics. The platelet is an anucleate cell with several features that render it suitable for chemical genetic analysis. This review addresses the benefits and challenges of chemical genetics using platelets as a model system.

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