Cross-ligation and exchange reaction of RNA catalyzed by hairpin ribozymes
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- PMID: 1283911
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Cross-ligation and exchange reaction of RNA catalyzed by hairpin ribozymes
Nucleic Acids Symp Ser.
1992.
Abstract
The catalytic domain in the minus strand of the satellite RNA of tobacco ringspot virus (sTobRV(-)) assumes a hairpin-like secondary structure. This ribozyme catalyzes a cross-ligation reaction between substrate RNAs of different lengths. We constructed ribozymes to probe the activities of ligation and RNA fragment exchange.
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