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. 1992:(27):43-4.

Cross-ligation and exchange reaction of RNA catalyzed by hairpin ribozymes

Y Komatsu  1 , M Koizumi, A Sekiguchi, E Ohtsuka
Affiliations
  • PMID: 1283911

Cross-ligation and exchange reaction of RNA catalyzed by hairpin ribozymes

Y Komatsu et al. Nucleic Acids Symp Ser. 1992.

Abstract

The catalytic domain in the minus strand of the satellite RNA of tobacco ringspot virus (sTobRV(-)) assumes a hairpin-like secondary structure. This ribozyme catalyzes a cross-ligation reaction between substrate RNAs of different lengths. We constructed ribozymes to probe the activities of ligation and RNA fragment exchange.

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