Severe acute respiratory syndrome (SARS)
- PMID: 12841401
- PMCID: PMC7091342
- DOI: 10.1007/BF02723614
Severe acute respiratory syndrome (SARS)
Abstract
Several cases of life threatening respiratory disease with no identifiable cause were reported from Guangdong Province, China; these were soon followed by reports from many other countries. The disease was named as severe acute respiratory syndrome (SARS). A novel coronavirus, isolated from the respiratory secretions of patients, has been implicated in the causation of SARS. The modes of transmission include droplet spread, close contact, and Fomites; shedding of virus from respiratory tract is the primary mode of transmission. SARS clinically presents with high-grade fever, chills and rigors, myalgia, headache, cough with or without sputum production, dyspnea, and dizziness. Chest radiographs reveal unilateral or bilateral, predominantly peripheral, areas of consolidation progressing with in a short time of bilateral patchy consolidation. Preliminary reports suggest a milder illness in young children. The case definition of probable SARS cases, laboratory investigations and precautions for prevention of spread are discussed.
Similar articles
-
Update: outbreak of severe acute respiratory syndrome--worldwide, 2003.MMWR Morb Mortal Wkly Rep. 2003 Apr 4;52(13):269-72. MMWR Morb Mortal Wkly Rep. 2003. PMID: 12729074
-
From the Centers for Disease Control and Prevention. Update: outbreak of severe acute respiratory syndrome--worldwide, 2003.JAMA. 2003 Apr 23-30;289(16):2059-60. doi: 10.1001/jama.289.16.2059. JAMA. 2003. PMID: 12709450 No abstract available.
-
Children hospitalized with severe acute respiratory syndrome-related illness in Toronto.Pediatrics. 2003 Oct;112(4):e261. doi: 10.1542/peds.112.4.e261. Pediatrics. 2003. PMID: 14523209
-
Severe acute respiratory syndrome (SARS): breath-taking progress.J Med Microbiol. 2003 Aug;52(Pt 8):609-613. doi: 10.1099/jmm.0.05321-0. J Med Microbiol. 2003. PMID: 12867552 Review.
-
SARS: a new infectious disease for a new century.Aust Fam Physician. 2003 Oct;32(10):779-83. Aust Fam Physician. 2003. PMID: 14596069 Review.
Cited by
-
Inhibition of infection caused by severe acute respiratory syndrome-associated coronavirus by equine neutralizing antibody in aged mice.Int Immunopharmacol. 2007 Mar;7(3):392-400. doi: 10.1016/j.intimp.2006.10.009. Epub 2006 Nov 27. Int Immunopharmacol. 2007. PMID: 17276898 Free PMC article.
References
-
- World Health Organization. Cummulative number of reported probable cases of Severe Acute Respiratory Syndrome (SARS). (Accessed May 5, 2003 at http:// www.who.int/csr/sarscountry/2003_05_03/en/).
-
- Drosten C, Günther S, Preiser W, van der Werf S, Brodt H, Becker Set al. Identification of a novel coronavirus in patients with Severe Acute Respiratory Syndrome. Article published at www.nejm.org on April 10, 2003. - PubMed
-
- Poutanen SM, Low DE, Henry B, Finkelstein S, Rose D, Green Ket al. Identification of Severe Acute Respiratory Syndrome in Canada. Article published at www.nejm.org on March 31, 2003. - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Miscellaneous