Systemic plus topical antibiotic prophylaxis reduced acquired infections and organ dysfunction in critically ill adults

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Mary-Anne Aarts et al. ACP J Club. 2003 Jul-Aug.

. 2003 Jul-Aug;139(1):6.

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Comment on

Influence of combined intravenous and topical antibiotic prophylaxis on the incidence of infections, organ dysfunctions, and mortality in critically ill surgical patients: a prospective, stratified, randomized, double-blind, placebo-controlled clinical trial.
Krueger WA, Lenhart FP, Neeser G, Ruckdeschel G, Schreckhase H, Eissner HJ, Forst H, Eckart J, Peter K, Unertl KE. Krueger WA, et al. Am J Respir Crit Care Med. 2002 Oct 15;166(8):1029-37. doi: 10.1164/rccm.2105141. Am J Respir Crit Care Med. 2002. PMID: 12379544 Clinical Trial.