An update on the genetics of Gilles de la Tourette syndrome
- PMID: 12842226
- DOI: 10.1016/s0022-3999(02)00586-x
An update on the genetics of Gilles de la Tourette syndrome
Abstract
Objectives: To summarize the current data suggesting that Gilles de la Tourette syndrome (GTS) is inherited and genetic.
Methods: The extant literature on family studies, segregation analyses, candidate genes studies and linkage studies of GTS was reviewed and summarized.
Results and conclusions: There is considerable data that suggests that: (1). genetic factors play an important role in the manifestation of GTS; (2). several genes are important with some possibly having major effect; and (3). several regions of the genome have been identified as potential locations of these susceptibility genes.
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