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Case Reports
. 2003 Jul 8;61(1):99-101.
doi: 10.1212/01.wnl.0000072482.70963.d7.

Gaucher's disease with Parkinson's disease: clinical and pathological aspects

B Bembi  1 , S Zambito Marsala, E Sidransky, G Ciana, M Carrozzi, M Zorzon, C Martini, M Gioulis, M G Pittis, L Capus
Affiliations
Case Reports

Gaucher's disease with Parkinson's disease: clinical and pathological aspects

B Bembi et al. Neurology. .

Abstract

The association between type 1 Gaucher disease and PD has been reported in the literature. The clinical picture is characterized by the predominance of bilateral akinetic-rigid signs and poor response to levodopa therapy. The authors describe four patients (two siblings) with type 1 Gaucher disease presenting with the following signs of typical PD: asymmetric onset of rigidity, resting tremor, bradykinesia, and a favorable response to Parkinson therapies.

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