[Corneal transplantation]
- PMID: 1285478
[Corneal transplantation]
Abstract
In contrast to organ transplantations corneal grafts are tissue transplantations with the advantage of a minority of immune stimulating cells. The incidence of allograft rejections is greater in penetrating grafts than in lamellar grafts because of endothelial immune reactions. The decompensation of the graft is caused by the damage of the endothelial layer. The influence of HLA-A, -B and -DR matching is proven in case of vascularised cornea or of repeated perforating keratoplasty. The introduction of the immunosuppressive therapy with Ciclosporin A was successful in maintaining a clear graft.
Similar articles
-
[Clinical study on the endothelial immune rejection after penetrating keratoplasty].Zhonghua Yan Ke Za Zhi. 2005 Feb;41(2):145-9. Zhonghua Yan Ke Za Zhi. 2005. PMID: 15840342 Chinese.
-
[Acute and chronic immune reactions after penetrating keratoplasty with normal immune risk].Klin Monbl Augenheilkd. 1997 Mar;210(3):139-43. doi: 10.1055/s-2008-1035032. Klin Monbl Augenheilkd. 1997. PMID: 9206744 German.
-
[Chronic endothelial cell loss of the graft after penetrating keratoplasty: influence of endothelial cell migration from graft to host].Klin Monbl Augenheilkd. 2002 Jun;219(6):410-6. doi: 10.1055/s-2002-32876. Klin Monbl Augenheilkd. 2002. PMID: 12136435 German.
-
Corneal graft rejection.Surv Ophthalmol. 2007 Jul-Aug;52(4):375-96. doi: 10.1016/j.survophthal.2007.04.008. Surv Ophthalmol. 2007. PMID: 17574064 Review.
-
[Rejection of corneal allografts].J Fr Ophtalmol. 2011 May;34(5):331-48. doi: 10.1016/j.jfo.2011.02.001. Epub 2011 Apr 14. J Fr Ophtalmol. 2011. PMID: 21492957 Review. French.
Publication types
MeSH terms
LinkOut - more resources
Medical
Research Materials