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. 2003 Aug;77(15):8181-6.
doi: 10.1128/jvi.77.15.8181-8186.2003.

Host factors in positive-strand RNA virus genome replication

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Host factors in positive-strand RNA virus genome replication

Paul Ahlquist et al. J Virol. 2003 Aug.
No abstract available

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Figures

FIG. 1.
FIG. 1.
Highly simplified schematic of major steps in positive-strand RNA virus genome replication. Arrows 1 and 2 depict the sequential use of the infecting, positive-strand genomic RNA as a template first for translation and then for RNA replication. As discussed in the text, precedents exist for host factor involvement in most steps shown. Based on examples cited in this review, sample host factors (HF) are shown interacting with viral RNA, viral RNA replication proteins, and host membranes. Some host factors may be associated with viral components only transiently during particular steps of the replication process.

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