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Review
. 2003 Jul;112(2):147-9.
doi: 10.1172/JCI19190.

Osteopontin: a bridge between bone and the immune system

Ellen M Gravallese  1
Affiliations
Review

Osteopontin: a bridge between bone and the immune system

Ellen M Gravallese. J Clin Invest. 2003 Jul.

Erratum in

  • J Clin Invest. 2003 Aug;112(4):627

Abstract

The molecular mechanisms underlying the putative role of osteopontin in the chronic inflammatory disease rheumatoid arthritis are unclear. A study in a murine model of arthritis now demonstrates that a specific antibody directed against the exposed osteopontin epitope SLAYGLR is capable of preventing inflammatory cell infiltration in arthritic joints.

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References

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