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Review
. 2003 Aug;133(2):156-9.
doi: 10.1046/j.1365-2249.2003.02230.x.

Deficiencies of the complement MAC II gene cluster (C6, C7, C9): is subtotal C6 deficiency of particular evolutionary benefit?

R Würzner
Review

Deficiencies of the complement MAC II gene cluster (C6, C7, C9): is subtotal C6 deficiency of particular evolutionary benefit?

R Würzner. Clin Exp Immunol. 2003 Aug.
No abstract available

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Figures

Fig. 1
Fig. 1
Locations of all known C6, C7 or C9 mutations leading to deficiencies (to June 2003) in relation to the modules (indicated in the box). Deletions (?), boundary mutations, generating nonsense intron sequence till a stop codon is reached (#), and amino acid substitutions (A111B) are indicated. In addition, mutations leading to subtotal deficiency are boxed.
See this image and copyright information in PMC

Comment on

  • Complement component C7 deficiency in a Spanish family.
    Vázquez-Bermúdez MF, Barroso S, Walter K, Alvarez AJ, Alarcón A, López-Trascasa M, Wichmann I, Aguilar F, Núñez-Roldán A, Sánchez B. Vázquez-Bermúdez MF, et al. Clin Exp Immunol. 2003 Aug;133(2):240-6. doi: 10.1046/j.1365-2249.2003.02186.x. Clin Exp Immunol. 2003. PMID: 12869030 Free PMC article.

References

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    1. Prodinger WM, Würzner R, Stoiber H, Dierich MP. Complement. In: Paul WE, editor. Fundamental Immunology. Philadelphia: Lippincott-Raven; 2003. pp. 1077–103.
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