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Case Reports
. 2003 Jul-Aug;20(4):323-6.
doi: 10.1046/j.1525-1470.2003.20410.x.

Olmsted syndrome: the clinical spectrum of mutilating palmoplantar keratoderma

Fabiane N Bergonse  1 , Suzy M Rabello, Rodrigo L Barreto, Ricardo Romiti, Marcello Menta S Nico, Valéria Aoki, Vitor Manoel S Reis, Evandro A Rivitti
Affiliations
Case Reports

Olmsted syndrome: the clinical spectrum of mutilating palmoplantar keratoderma

Fabiane N Bergonse et al. Pediatr Dermatol. 2003 Jul-Aug.

Abstract

Olmsted syndrome is a rare variety of transgredient palmoplantar keratoderma with an undefined inheritance pattern. It starts in the neonatal period or in childhood and has a progressive and extremely disabling course. We report two new, unrelated patients with Olmsted syndrome, one with the early signs and symptoms of the disorder, the other showing the full-blown spectrum of the syndrome during a 30-year follow-up period.

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