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Comparative Study
. 2003 Aug 1;188(3):424-7.
doi: 10.1086/376531. Epub 2003 Jul 10.

Susceptibility of human T cell leukemia virus type I to nucleoside reverse transcriptase inhibitors

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Comparative Study

Susceptibility of human T cell leukemia virus type I to nucleoside reverse transcriptase inhibitors

Shawn A Hill et al. J Infect Dis. .

Abstract

A single-cycle infection assay with recombinant viral vectors was developed to study human T cell leukemia virus type I (HTLV-I) replication and its inhibition by antiviral agents. The susceptibility of HTLV-I to 6 nucleoside reverse-transcriptase inhibitors was examined. HTLV-I replication was inhibited by tenofovir, abacavir, lamivudine, zalcitabine, stavudine, and zidovudine.

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