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Clinical Trial
. 2003 Aug;88(8):719-23.
doi: 10.1136/adc.88.8.719.

Nebuliser hood compared to mask in wheezy infants: aerosol therapy without tears!

I Amirav  1 , I Balanov, M Gorenberg, D Groshar, A S Luder
Affiliations
Clinical Trial

Nebuliser hood compared to mask in wheezy infants: aerosol therapy without tears!

I Amirav et al. Arch Dis Child. 2003 Aug.

Abstract

Background: Small volume nebulisers (SVNs) with masks commonly provide aerosol therapy for infants with lung diseases. However, infants and toddlers are often disturbed by and thus reject masks.

Aims: To compare the lung deposition efficiency of the "usual" SVN aerosol mask and a prototype hood attached to an SVN. The advantage of the hood is that no mask is needed and medication can readily be administered during sleep.

Methods: 99mTc salbutamol solution was administered at random by SVN plus mask or hood to 14 wheezy infants (mean age 8 (SD 5) months). The dose and distribution of salbutamol were evaluated using gamma scintigraphy. Clinical response, tolerability by the infants, and parent preference were also compared.

Results: Mean total lung deposition was 2.6% with the hood and 2.4% with the mask (p > 0.05). Variability with the mask was greater than with the hood (coefficient of variation (CoV) 54% v 39%). Both treatments provided similar clinical benefit and side effects as reflected in improved oxygen saturation, reduced respiratory frequency, and increased heart rate. Infants accepted the hood better than the mask and there was a positive correlation between poor acceptance and upper airways and stomach deposition for both treatment modalities. Parents preferred the hood treatments.

Conclusions: Aerosol therapy by hood is as efficient as by mask but provides a better therapeutic index. It is much better tolerated by infants and preferred by parents. Hood nebulisation is a simple and patient friendly mode of aerosol therapy in wheezy infants.

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Figures

Figure 1
Figure 1
Infant undergoing hood nebuliser treatment.
Figure 2
Figure 2
Scans of one of the patients obtained during hood and mask treatments. Body and lung markings are superimposed for clarity. Note the considerable deposition in the URT and GIT during the mask treatment.
Figure 3
Figure 3
Comparison of scintigraphic URT and GIT deposition data and behaviour index during hood and mask treatments.
See this image and copyright information in PMC

Comment in

References

    1. Ann Allergy. 1990 Apr;64(4):383-7 - PubMed
    1. Pediatr Pulmonol. 1989;6(4):263-7 - PubMed
    1. Arch Dis Child. 1992 May;67(5):586-91 - PubMed
    1. J Nucl Med. 1992 Sep;33(9):1717-9 - PubMed
    1. Crit Rev Ther Drug Carrier Syst. 1993;10(1):65-109 - PubMed

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