Review
doi: 10.1007/s00216-003-2101-0.
Epub 2003 Jul 19.
Present and future of surface plasmon resonance biosensors
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- PMID: 12879189
- DOI: 10.1007/s00216-003-2101-0
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Review
Present and future of surface plasmon resonance biosensors
Anal Bioanal Chem.
2003 Oct.
Abstract
Surface plasmon resonance (SPR) biosensors are optical sensors exploiting special electromagnetic waves-surface plasmon-polaritons-to probe interactions between an analyte in solution and a biomolecular recognition element immobilized on the SPR sensor surface. Major application areas include detection of biological analytes and analysis of biomolecular interactions where SPR biosensors provide benefits of label-free real-time analytical technology. This paper reviews fundamentals of SPR affinity biosensors and discusses recent advances in development and applications of SPR biosensors.
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