doi: 10.1021/np020356j.
Cytotoxic diterpenes from Scoparia dulcis
Affiliations
- PMID: 12880314
- DOI: 10.1021/np020356j
Item in Clipboard
Cytotoxic diterpenes from Scoparia dulcis
J Nat Prod.
2003 Jul.
Abstract
Four new labdane-derived diterpenes, iso-dulcinol (1), 4-epi-scopadulcic acid B (2), dulcidiol (4), and scopanolal (5), together with two known diterpenes, dulcinol/scopadulciol (3) and scopadiol (6), were isolated from the aerial parts of Scoparia dulcis. The structures were determined by extensive NMR studies. The crude extracts as well as the pure diterpenes showed cytotoxicity against a panel of six human stomach cancer cell lines.
Similar articles
-
Bioactive diterpenoids, a new jatrophane and two ent-abietanes, and other constituents from Euphorbia pubescens.J Nat Prod. 2004 May;67(5):902-4. doi: 10.1021/np0400048. J Nat Prod. 2004. PMID: 15165162
-
New diterpenes from Croton insularis.J Nat Prod. 2004 Apr;67(4):685-8. doi: 10.1021/np030423p. J Nat Prod. 2004. PMID: 15104505
-
Labdane diterpenes from Aster spathulifolius and their cytotoxic effects on human cancer cell lines.J Nat Prod. 2005 Oct;68(10):1471-4. doi: 10.1021/np058044e. J Nat Prod. 2005. PMID: 16252909
-
[Investigation on traditional medicines of Guarany Indio and studies on diterpenes from Scoparia dulcis].Yakugaku Zasshi. 2011;131(9):1259-69. doi: 10.1248/yakushi.131.1259. Yakugaku Zasshi. 2011. PMID: 21881299 Review. Japanese.
-
Bioactive Pimarane-Type Diterpenes from Marine Organisms.Chem Biodivers. 2018 Jan;15(1). doi: 10.1002/cbdv.201700276. Epub 2017 Dec 21. Chem Biodivers. 2018. PMID: 28737020 Review.
Cited by
-
Bioactivity Evaluation of Plant Extracts Used in Indigenous Medicine against the Snail, Biomphalaria glabrata, and the Larvae of Aedes aegypti.Evid Based Complement Alternat Med. 2012;2012:846583. doi: 10.1155/2012/846583. Epub 2011 Dec 11. Evid Based Complement Alternat Med. 2012. PMID: 22194773 Free PMC article.
-
Indigenous Uses, Phytochemical Analysis, and Anti-Inflammatory Properties of Australian Tropical Medicinal Plants.Molecules. 2022 Jun 15;27(12):3849. doi: 10.3390/molecules27123849. Molecules. 2022. PMID: 35744969 Free PMC article. Review.
-
Isolation of a new iso-quinoline alkaloid and cytotoxicity studies of pure compounds and crude extracts of Ravenia spectabilis engl.Heliyon. 2024 Jul 11;10(14):e34508. doi: 10.1016/j.heliyon.2024.e34508. eCollection 2024 Jul 30. Heliyon. 2024. PMID: 39113993 Free PMC article.
-
Green Silver Nanoparticles Formed by Phyllanthus urinaria, Pouzolzia zeylanica, and Scoparia dulcis Leaf Extracts and the Antifungal Activity.Nanomaterials (Basel). 2020 Mar 17;10(3):542. doi: 10.3390/nano10030542. Nanomaterials (Basel). 2020. PMID: 32192177 Free PMC article.
-
A New Diterpenoid of Indonesian Scoparia dulcis Linn: Isolation and Cytotoxic Activity against MCF-7 and T47D Cell Lines.Molecules. 2023 Aug 9;28(16):5960. doi: 10.3390/molecules28165960. Molecules. 2023. PMID: 37630212 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
