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. 1992 Oct;114(10):378-80.

[Cerebokrast as a corrector of postischemic phenomena in acute transient cerebral ischemia]

[Article in Russian]
T G Bazhenova, M B Plotnikov, T M Plotnikova, A S Saratikov
  • PMID: 1288692

[Cerebokrast as a corrector of postischemic phenomena in acute transient cerebral ischemia]

[Article in Russian]
T G Bazhenova et al. Biull Eksp Biol Med. 1992 Oct.

Abstract

Acute cerebral ischemia in cats (both carotid arteries occlusion during 30 min after permanent occlusion of both vertebral arteries) was accompanied by postischemic hypoperfusion and hypo-oxygenation of the cerebral tissue. Intravenous infusion of cerebrocrast (1 micrograms.kg-1.min-1 during 60 min) prevented manifestation of the postischemic phenomena. Antihypoxic effect of cerebrocrast involved the cerebral blood flow increase, brain oxygen consumption lowering and Hb-O2-affinity decrease.

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