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. 2003 Aug 6;125(31):9282-3.
doi: 10.1021/ja0356333.

Palladium-catalyzed [3+2] intramolecular cycloaddition of alk-5-ynylidenecyclopropanes: a rapid, practical approach to bicyclo[3.3.0]octenes

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Palladium-catalyzed [3+2] intramolecular cycloaddition of alk-5-ynylidenecyclopropanes: a rapid, practical approach to bicyclo[3.3.0]octenes

Alejandro Delgado et al. J Am Chem Soc. .

Abstract

Readily accessible hex-5-ynylidenecyclopropane derivatives cycloisomerize to bicyclic five-membered carbocycles upon heating with catalytic amounts of a palladium complex.

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