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. 1992 Jun;8(3):104-8.
doi: 10.1111/j.1600-9657.1992.tb00445.x.

In vitro solubility of human pulp tissue in calcium hydroxide and sodium hypochlorite

M Andersen  1 , A Lund, J O Andreasen, F M Andreasen
Affiliations

In vitro solubility of human pulp tissue in calcium hydroxide and sodium hypochlorite

M Andersen et al. Endod Dent Traumatol. 1992 Jun.

Abstract

The tissue solvent capacity of a 2% stabilized sodium hypochlorite solution (Milton) and a commercial calcium hydroxide solution (Calasept) was examined under in vitro conditions where autolyzed human pulp fragments weighing approximately 0.0065 g were immersed in these solutions at 37 degrees C for periods of up to 10 days. It appeared that sodium hypochlorite was able to dissolve half the volume of pulp tissue within 1 h and the remaining tissue after 2-2 1/2 h. Calcium hydroxide dissolved half the pulp volume within 2 h, whereas it took 1 week for the remaining tissue to dissolve. These findings support the use of sodium hypochlorite as an irrigation solution during canal preparation and calcium hydroxide as a canal dressing for the purpose of creating a canal free of pulp remnants before root filling.

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