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Case Reports
. 2003 Aug;49(2 Suppl Case Reports):S187-9.
doi: 10.1067/mjd.2003.339.

Neonatal pemphigus foliaceus

Affiliations
Case Reports

Neonatal pemphigus foliaceus

Ranella Hirsch et al. J Am Acad Dermatol. 2003 Aug.

Abstract

The term "pemphigus" refers to a group of diseases that are characterized by the presence of cutaneous or mucosal blisters and erosions, and antiepidermal autoantibodies. There are several case reports of neonatal pemphigus vulgaris in the literature. Although pemphigus foliaceus antibodies have been shown to cross the placenta, to our knowledge, this is only the second reported case of neonatal pemphigus foliaceus. The proposed mechanism of disease transfer is the passive transfer of maternal IgG antibodies across the placenta.

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