Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2003 Sep;47(3):209-20.

Radiopharmaceuticals for targeting the angiogenesis marker alpha(v)beta(3)

Affiliations
  • PMID: 12897712
Free article
Review

Radiopharmaceuticals for targeting the angiogenesis marker alpha(v)beta(3)

P McQuade et al. Q J Nucl Med. 2003 Sep.
Free article

Abstract

A common feature of solid tumors is the formation of new blood vessels (angiogenesis) within the tumor. A receptor called alpha(v)beta(3) is found on endothelial cells lining newly growing blood vessels at a higher density than on mature blood vessels. This receptor may provide a target for radioligands to permit imaging of a wide variety of solid tumors. The radioligands may range from macromolecules such as native ligands or monoclonal antibodies, to small proteins to very small peptides. The differing characteristics of these bio-molecules have an affect on target delivery and clearance time.

PubMed Disclaimer

Similar articles

Cited by

MeSH terms

LinkOut - more resources