Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2003:164:353-6.
doi: 10.1007/978-3-642-55580-0_25.

Prospects for vitamin D receptor modulators as candidate drugs for cancer and (auto)immune diseases

Roger Bouillon  1 , Annemieke Verstuyf, Lieve Verlinden, Guy Eelen, Chantal Mathieu
Affiliations
Review

Prospects for vitamin D receptor modulators as candidate drugs for cancer and (auto)immune diseases

Roger Bouillon et al. Recent Results Cancer Res. 2003.

Abstract

The development of less calcemic vitamin D analogs creates possible therapeutic applications for immune modulation (e.g., autoimmune diseases and graft rejection), inhibition of cell proliferation and induction of cell differentiation (e.g., cancer). Recently more insight was obtained in the mechanism of action of the analogs at the biological and molecular level. Critical remarks are summarized on why the step towards the clinic has not yet been taken and how better selective vitamin D receptor modulators could be designed.

PubMed Disclaimer

MeSH terms