doi: 10.1093/nass/44.1.15.
New thermodynamic characterization and transition mechanism of DNA duplex formation
Affiliations
- PMID: 12903246
- DOI: 10.1093/nass/44.1.15
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New thermodynamic characterization and transition mechanism of DNA duplex formation
Nucleic Acids Symp Ser.
2000.
Abstract
A new transition mechanism of DNA duplex association was proposed and a segregated transition model (STM) was further derived. The experimental results in various molar ratios showed that the duplex association transition is imperfect and the thermodynamic properties and self-transition behavior of single strands exert a significant influence on DNA duplex formation.
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