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. 2000:(44):15-6.
doi: 10.1093/nass/44.1.15.

New thermodynamic characterization and transition mechanism of DNA duplex formation

P Wu  1 , N Sugimoto
Affiliations

New thermodynamic characterization and transition mechanism of DNA duplex formation

P Wu et al. Nucleic Acids Symp Ser. 2000.

Abstract

A new transition mechanism of DNA duplex association was proposed and a segregated transition model (STM) was further derived. The experimental results in various molar ratios showed that the duplex association transition is imperfect and the thermodynamic properties and self-transition behavior of single strands exert a significant influence on DNA duplex formation.

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