doi: 10.1021/ja034912n.
Mixed-element capture agents: a simple strategy for the construction of synthetic, high-affinity protein capture ligands
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- PMID: 12903996
- DOI: 10.1021/ja034912n
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Mixed-element capture agents: a simple strategy for the construction of synthetic, high-affinity protein capture ligands
J Am Chem Soc.
.
Abstract
Demonstration of a simple strategy to generate synthetic high-affinity protein capture agents of practical utility for protein-detecting microarrays. The model study highlights capture of the MBP-Mdm2 fusion protein on a solid support by a linear sequence of peptides that bind to the two individual polypeptide chains.
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