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Clinical Trial
. 2003 Aug 15;37(4):528-32.
doi: 10.1086/376914. Epub 2003 Jul 30.

Asymptomatic infection with Borrelia burgdorferi

Allen C Steere  1 , Vijay K Sikand, Robert T Schoen, John Nowakowski
Affiliations
Clinical Trial

Asymptomatic infection with Borrelia burgdorferi

Allen C Steere et al. Clin Infect Dis. .

Abstract

The natural history of asymptomatic seroconversion to Borrelia burgdorferi has been unclear. We report here, on the basis of a post hoc assessment, the frequency and outcome of asymptomatic seroconversion to B. burgdorferi in participants of a large Lyme disease vaccine trial. We show that infection with B. burgdorferi may be asymptomatic but that asymptomatic infection is unusual in the United States.

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