[Weekly cyclophosphamide pulse therapy combined with corticosteroids in the treatment of pemphigus]
- PMID: 12905897
[Weekly cyclophosphamide pulse therapy combined with corticosteroids in the treatment of pemphigus]
Abstract
Objective: To investigate the better regimen of combined cyclophosphamide pulse therapy with corticosteroids in the treatment of Pemphigus.
Methods: Intravenous cyclophosphamide was given weekly in a dosage of 600 mg to those Pemphigus patients whose conditions couldn't be improved by corticosteroids (oral prednisone 1.2-1.5 mg/kg/d) alone.
Results: Ten patients with Pemphigus received weekly cyclophosphamide therapy in addition to corticosteroid. Patients conditions improved quickly, without side effects.
Conclusions: Cyclophosphamide weekly pulse therapy combined with corticosteroids is a good regimen in the treatment of Pemphigus.
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