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Review
. 2003 Aug 5;13(15):R611-3.
doi: 10.1016/s0960-9822(03)00529-3.

Receptor-ligand binding: 'catch' bonds finally caught

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Free article
Review

Receptor-ligand binding: 'catch' bonds finally caught

Konstantinos Konstantopoulos et al. Curr Biol. .
Free article

Abstract

Leukocyte recruitment to sites of inflammation is initiated by the selectin family of adhesion receptors. Recent research reveals that P-selectin binding to its ligand exhibits 'catch' to 'slip' bond transition that may help explain the shear threshold phenomenon.

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