Inappropriate ileal conservation of bile acids in cholestatic liver disease: homeostasis gone awry
- PMID: 12912852
- PMCID: PMC1773777
- DOI: 10.1136/gut.52.9.1239
Inappropriate ileal conservation of bile acids in cholestatic liver disease: homeostasis gone awry
Comment on
-
Intestinal absorption of the bile acid analogue 75Se-homocholic acid-taurine is increased in primary biliary cirrhosis, and reverts to normal during ursodeoxycholic acid administration.Gut. 2003 Sep;52(9):1371-5. doi: 10.1136/gut.52.9.1371. Gut. 2003. PMID: 12912872 Free PMC article.
References
-
- Hofmann AF. Bile acids: their continuing importance in liver and intestinal disease. Arch Int Med 1999;159:2647–58. - PubMed
-
- Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem 2003 (in press). - PubMed
-
- Hofmann AF. Intestinal absorption of bile acids and biliary constituents: the intestinal component of the enterohepatic circulation and the integrated system. In: Johnson LR, Alpers DH, Christensen J, et al, eds. Physiology of the gastrointestinal tract, vol 2, 3rd edn. New York: Raven Press, 1994:1845–65.
-
- Vlahcevic ZR, Pandak WM, Stravitz RT. Regulation of bile acid biosynthesis. Gastroenterol Clin North Am 1999;28:1–25. - PubMed
-
- Makashima J, Okamoto AY, Repa JJ, et al. Identification of a nuclear receptor for bile acids. Science 1999;284:1285–6. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources