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Comparative Study
. 2003 Sep-Oct;38(5):446-9.
doi: 10.1093/alcalc/agg110.

Serotonin transporter promoter polymorphism and differences in alcohol consumption behaviour in a college student population

Aryeh I Herman  1 , John W Philbeck, Nicholas L Vasilopoulos, Paolo B Depetrillo
Affiliations
Comparative Study

Serotonin transporter promoter polymorphism and differences in alcohol consumption behaviour in a college student population

Aryeh I Herman et al. Alcohol Alcohol. 2003 Sep-Oct.

Abstract

Aims and methods: In the present study, differences in alcohol consumption behaviour associated with the presence of the short variant (S) of the serotonin transporter promoter polymorphism (5-HTTLPR) was investigated in a Caucasian subset (n = 204) of 268 college students.

Results: Students who were homozygous for the S allele were more likely to engage in binge-drinking behaviour, drank more alcohol per occasion, and reported drinking to get drunk more often.

Conclusions: In this Caucasian sample, the 5-HTTLPR strongly influences alcohol consumption in late pubescence.

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