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. 2003 May;142(4):146-50.

Synthesis and antibacterial activity of 1,3-diarylpyrimido[4,5-d]pyrimidines

J Cieplik  1 , J Pluta, O Gubrynowicz
Affiliations
  • PMID: 12918222

Synthesis and antibacterial activity of 1,3-diarylpyrimido[4,5-d]pyrimidines

J Cieplik et al. Boll Chim Farm. 2003 May.

Abstract

This paper describes the synthesis of 4,5-diaminoderivatives of pyrimidine and pyrimido [4,5-d] pyrimidines and evaluation of their antibacterial activity on 9 selected bacterial species relatif the changes in the chemical structure to an increase in the bioactive properties.

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