A perceived cluster of amyotrophic lateral sclerosis cases in a Massachusetts community
- PMID: 1291891
- DOI: 10.1159/000110941
A perceived cluster of amyotrophic lateral sclerosis cases in a Massachusetts community
Abstract
We investigated a report of a perceived cluster of amyotrophic lateral sclerosis (ALS) in Middleborough, Mass. Although an increase in ALS incidence was observed [2.51 deaths/100,000 person-years (p-y)], relative to the statewide rate over the years 1969-1985 (1.26/100,000 p-y), it was not statistically significant at the 95% confidence level. Problems in evaluating possible neurological disease clusters and their association with environmental exposures are presented.
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