Review
doi: 10.1038/ng1215.
Chromosome aberrations in solid tumors
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- PMID: 12923544
- DOI: 10.1038/ng1215
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Review
Chromosome aberrations in solid tumors
Nat Genet.
2003 Aug.
Abstract
Chromosome aberrations in human solid tumors are hallmarks of gene deregulation and genome instability. This review summarizes current knowledge regarding aberrations, discusses their functional importance, suggests mechanisms by which aberrations may form during cancer progression and provides examples of clinical advances that have come from studies of chromosome aberrations.
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