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. 2003 Sep;91(2):166-70.
doi: 10.1007/s00436-003-0952-0. Epub 2003 Aug 16.

TcArf1: a Trypanosoma cruzi ADP-ribosylation factor

Alexandre de Sá-Freire  1 , José Luciano Nepomuceno-Silva, Júlio César da Paixão, Sérgio Maurício de Mendonça, Luiz Dione Barbosa de Melo, Ulisses Gazos Lopes
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TcArf1: a Trypanosoma cruzi ADP-ribosylation factor

Alexandre de Sá-Freire et al. Parasitol Res. 2003 Sep.

Abstract

Arfs (ADP-ribosylation factors) are conserved GTP-binding proteins involved in the control of coatomers assembling in budding vesicles in the eukaryotic secretory pathway and during some endocytic events. Here, we describe the gene for an Arf-homologue from the unicellular kinetoplastid parasite Trypanosoma cruzi, named TcArf1. TcArf1 is present in a discrete copy number in the T. cruzi genome and is expressed as a 1-kb transcript in the three main life forms of the parasite. Increased mRNA expression in epimastigotes may correlate with abundant protein biosynthesis and endocytosis in this stage.

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References

    1. J Cell Sci. 2001 Jul;114(Pt 14):2617-26 - PubMed
    1. Mem Inst Oswaldo Cruz. 1999;94 Suppl 1:429-32 - PubMed
    1. J Biol Chem. 1992 May 15;267(14):9654-62 - PubMed
    1. Biochim Biophys Acta. 1998 Nov 8;1442(2-3):347-52 - PubMed
    1. Mol Cell Biol. 1990 Dec;10(12):6690-9 - PubMed

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