Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2003 Nov;377(5):820-5.
doi: 10.1007/s00216-003-2144-2. Epub 2003 Aug 19.

Microchip PCR

L J Kricka  1 , P Wilding
Affiliations
Review

Microchip PCR

L J Kricka et al. Anal Bioanal Chem. 2003 Nov.

Abstract

Miniaturization of genetic tests has become an important goal. This review surveys the current progress towards the miniaturization of tests based on the polymerase chain reaction (PCR). It examines the different types of PCR microchip designs, fabrication methods,and the components of a microchip PCR device. It also discusses the problems attributable to surface chemistry of microchip components (inhibition of PCR), and the static and dynamic surface passivation strategies developed for the solution of these difficulties

PubMed Disclaimer

MeSH terms

LinkOut - more resources