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. 2003 Jul;14(7):448-53.
doi: 10.1007/s00335-002-2261-9.

A major locus conferring susceptibility to infection by Streptococcus pneumoniae in mice

Paul Denny  1 , Elaine Hopes, Neill Gingles, Karl W Broman, William McPheat, John Morten, Janet Alexander, Peter W Andrew, Steve D M Brown
Affiliations

A major locus conferring susceptibility to infection by Streptococcus pneumoniae in mice

Paul Denny et al. Mamm Genome. 2003 Jul.

Abstract

We have studied the genetics of susceptibility to infection by Streptococcus pneumoniae in mice. Linkage analysis of the F(2) generation from a cross between resistant BALB/cO1aHsd and susceptible CBA/CaO1aHsd strains allowed us to map a major locus controlling the development of bacteremia and survival after intranasal infection.

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