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. 1992 Nov;19(11):648-51.
doi: 10.1111/j.1346-8138.1992.tb03750.x.

The growth regulation of keratinocytes

K Hashimoto  1 , K Yoshikawa
Affiliations

The growth regulation of keratinocytes

K Hashimoto et al. J Dermatol. 1992 Nov.

Abstract

Taken together, all these results suggest that TGF-alpha and amphiregulin are the major growth factors for positive growth control, although we don't know which plays the central role. For negative growth control, TGF-beta is the major factor. However, it remains to be solved which isoform of TGF-beta is naturally involved in keratinocyte growth regulation.

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